Custom Peptides
Cayman Chemical 6-EAPBhydrochlorIde 10mg
An analytical reference standard categorized as a benzofuran; intended for research and forensic applications
Cayman Chemical BMK ethyl glycIdate 10mg
An analytical reference standard categorized as a precursor in the synthesis of phenylacetone; intended for research and forensic applications
Cayman Chemical Linolenoyl Ethanolamide 10mg
A member of the family of fatty N-acyl ethanolamines collectively called endocannabinoids
Cayman Chemical 4DeoxypyrIdoxIn PhosphAT 10mg
A vitamin B6 analog and an inhibitor of S1P lyase; induces accumulation of [3H]dhS1P in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50s = 100 µM in the absence and presence of vitamin B6, respectively)
Cayman Chemical S-PhenylcysteIn 10mg
An adduct; formed by the binding of benzene oxide to cysteine residues in hemoglobin; has been found in red blood cells isolated from benzene-exposed rats and mice
Cayman Chemical DehydrolIthocholIc AcId 10mg
A major metabolite of lithocholic acid; formed from LCA by CYP3A4; an agonist of TGR5 (EC50 = 0.27 μM), VDR (EC50 = 3 μM), and FXR in cell-based reporter assays; binds to human PXR (IC50 = 15 μM) and activates mouse and human PXRs in cell-based reporter assays at 100 μM; binds to RORγt (Kd = 1.13 μM for the recombinant human ligand-binding domain) and decreases its activity in a cell-based reporter assay at 10 μM; inhibits the differentiation of TH17 cells at 20 μM
Cayman Chemical ZofenoprIlcalcIum salt 10mg
A prodrug form of zofenoprilat; an ACE inhibitor (IC50 = 0.9 nM in heart tissue homogenates); reduces mean arterial blood pressure in 2K-1C rats and SHRs at 2.2, 6.6, and 22 mg/kg
Cayman Chemical L-Alanosine 10mg
An inhibitor of adenylosuccinate synthase (mean IC50 = 4.8 μM and 10 μM in T-ALL and CAK-1 cells, respectively); antineoplastic activity in MTAP deficient cells; disrupts de novo purine biosynthesis and inhibits cellular metabolism
Cayman Chemical Enoctabn 10mg
A prodrug form of cytarabine; resistant to deamination by cytidine deaminase; reduces the virus yield in the supernatant of CMV-infected Vero cells (EC90 = 0.5 UG/ml); inhibits viral DNA synthesis at 5 UG/ml; increases survival in an L1210 murine skin lymphocytic leukemia model
Cayman Chemical 2DeoxyadenosIn5OdIphos 10mg
A nucleotide diphosphate; inhibits the polymerization of ADP and CDP by E. coli or P. fluorescens polynucleotide phosphorylase at 0.23 mM; levels are increased in erythrocytes isolated from patients with adenosine deaminase deficiency and SCID
Cayman Chemical 2-OL-GalactopyrnosylorI 10mg
A flavonoid glycoside with anti-inflammatory activity; decreases LPS-induced production of NO, IL-6, and TNF-α in RAW 264.7 cells from 100-200 µM
Cayman Chemical N-ArachIdonylAmInobutyrIc 10mg
Several different arachidonoyl amino acids, including NAGABA, have been isolated and characterized from bovine brain. The glycine congener (NAGly) was found to suppress formalin-induced pain in rats. NAGABA also suppresses normal responses to pain, but has not yet been fully characterized.
Cayman Chemical MeIsoIndIgo 10mg
An anticancer agent; inhibits the growth of NB4, HL-60, and U937 leukemia and primary acute myeloid leukemia cells at 5 and 10 µM; induces apoptosis in leukemia cell lines, primary AML cells, and CML cells; decreases spleen size in an HL-60 mouse xenograft model of AML in a dose-dependent manner at 50-150 mg/kg
Cayman Chemical Catechn 10mg
A diastereoisomer of catechin having a trans 2S,3R configuration at the chiral center; a potent antioxidant that inhibits the free radical-induced oxidation of isolated LDL by AAPH