Custom Peptides
Cayman Chemical EmIdeltIdeacetate 10mg
A synthetic nonapeptide sedative; increases EEG delta activity and induces orthodox slow-wave sleep in free-moving rabbits at 30 nmol/kg, i.v.; increases NREM and total sleep in free-moving rats
Cayman Chemical D-noptern 10mg
An intermediate product in the synthetic pathway of biopterin that is released from macrophages upon immune stimulation with interferon-γ from activated T cells; routinely used as a biochemical tool to screen for and monitor the progression of certain diseases accompanied by hyperimmune stimulation
Cayman Chemical PravastatIn lacton 10mg
A metabolite of pravastatin; formed when pravastatin undergoes acid catalyzed non-enzymatic lactonization in the stomach
Cayman Chemical -5-trns Cloprostenol Isop 10mg
A more lipid soluble form of (+)-5-trans cloprostenol
Cayman Chemical 14-PentadecenoIc AcId 10mg
A 15-carbon, long-chain fatty acid that contains an alkene functional group on the terminal carbon of its aliphatic tail
Cayman Chemical Corynoln 10mg
An isoquinoline alkaloid with diverse biological activities; an inhibitor of acetylcholinesterase (IC50 = 30.6 µM); an inhibitor of BACE1 (IC50s = 33.59 and 89.07 µM for FRET and immobilized enzyme reactive assays, respectively); decreases LPS-induced NF-κB activation and reverses LPS-induced decreases in Nrf2 and HO-1 protein levels in HUVECs; increases the survival rate in a mouse model of LPS- and heat-killed E. coli-induced sepsis at 10, 20, and 40 mg/kg; selectively inhibits proliferation of B16/F10 mouse and A375 human melanoma cells (IC50s = 12.87 and 10.47 µM, respectively) over non-cancerous melanocytes (IC50 = 126.61 µM); reduces tumor growth in a B16/F10 mouse melanoma model at 20 mg/kg
Cayman Chemical 4methylNMethylbuphedron 10mg
A para-methyl analog of buphedrone with an aminomethyl addition; intended for research and forensic applications
Cayman Chemical 2Fluoro2deoxyarabInoCy 10mg
A fluorinated derivative of 2'-deoxycytidine; cytotoxic to CCRF-HSB-2, COLO 320DM, and MKN28 cancer cells (IC50s = 0.15, 0.19, and 29 UG/ml, respectively); inhibits HIV-1 replication in HIV-1-infected C8166 cells (IC50 = 0.7 µM); inhibits HSV-1 and HSV-2 replication in HSV-1- or HSV-2-infected Vero cells (IC50s = 0.12 and 0.3 µM, respectively)
Cayman Chemical RGDtargetd ProapoptoTCpep 10mg
A peptide; contains an integrin-binding cyclic region (CDCRGDCFC) and a region similar to a pro-apoptotic heptadimer sequence (klaklakklaklak), both of which are found in similar peptides
Cayman Chemical MavorIxafor 10mg
A CXCR4 antagonist (IC50 = 13 nM in a radioligand binding assay); selective for CXCR4 over CCR1, CCR2b, CCR4, CCR5, CXCR1, and CXCR2 (IC50s = >10 µM for all); reduces CXCL12-induced chemotaxis of CCRF-CEM T cells (IC50 = 19 nM); inhibits fusion of CHO-K1 cells expressing gp120 to P4 MAGI cells IC50 = 1.5 nM; decreases HIV-1 NL4.3 viral replication in MT-4 cells and isolated human PBMCs (IC50s = 2 and 9 nM, respectively)
Cayman Chemical AOD-9604acetate 10mg
A synthetic lipolytic peptide; decreases body weight, epididymal adipose tissue mass, and brown adipose tissue weight in ob/ob mice at 250 UG/kg per day; enhances cartilage regeneration in a rabbit model of collagenase-induced knee osteoarthritis
Cayman Chemical TazarotenIc AcId 10mg
An RAR agonist and an active metabolite of tazarotene; induces reporter gene expression in DK7-NR cells expressing human RARα, RARβ, or RARγ (EC50s = 11, 2.5, and 11 nM, respectively); reduces EAr edema in a PMA-induced mouse model of epidermal inflammation when applied topically at 0.1% w/w
Cayman Chemical DegarelIxacetate 10mg
A synthetic GNRHR antagonist (IC50 = 3 nM in HEK293 cells expressing the human receptor); inhibits the growth of WPMY-1, WPE1-NA22, BPH-1, and LNCaP prostate cell lines via caspase activation and induction of apoptosis (10 μM); decreases plasma testosterone levels in rats to castrate levels for the first 49 days post treatment (2 mg/kg); decreases tumor volume of Dunning R3327H prostate tumor flank implants in rats (1 mg/kg per month)